Welcome to the CLL Genome website


The Chronic Lymphocytic Leukemia (CLL) Genome Project aims to generate a comprehensive catalogue of genomic alterations involved in the development and progression of the disease. This information will improve our ability to diagnose and categorize the patients and will promote the advance in new therapeutic approaches. 

The CLL Genome Project, as a contributing member of the International Cancer Genome Consortium (ICGC), has the purposes of creating diagnostic tools, discovering therapeutic targets and developing new strategies that will allow a customized therapy for CLL in order to make it more precise and effective.


News: Researchers sequence the genome of more than 500 patients with leukemia and identify recurrent mutations in non-coding regions of the genome, providing novel clues about cancer development. This study forms part of the International Cancer Genome Consortium, and constitutes the first study to analyze 500 genomes of a single tumor. The study was published today, July 22nd of 2015, in the journal Nature and marks a milestone in the understanding of chronic lymphocytic leukemia. Press releases (englishspanish). Article.


ISCIII CLL Genome Project is funded by the Spanish Ministry of Economy and Competitivity through the Institute of Health Carlos III (ISCiii).